UK CLL Forum, UKCLLFORUM

FCR lite

Topic Made On: Jun 05, 2009 08:46pm
annjohnes

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Gender: Female
Posts: 7
Just wondered if anyone in the UK had tried or been offered FCR lite? and if so what dosage was used?
We are trying to find a less toxic way for next time round
Thanks
Ann




Replied On: Jun 08, 2009 10:50am
Robert Cork

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Gender: Male
Posts: 160
Ann

I am not aware of RFC Lite being extensively used in the UK, but there might be someone that was given the opportunity to give it ago.

I did find the following doses from one of the trials run in the US.
The monthly doses of fludarabine and cyclophosphamide were decreased from 25 to 20 mg/m2 and from 250 to 150 mg/m2, respectively, but the dose intensity of rituximab was increased to 500 mg/m2 every other week.

Regards

Robert



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