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Southampton scientists make major breakthrough in fighting leukaemia

Topic Made On: Dec 07, 2009 10:56am
Robert Cork

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I have just seen this:

Southampton scientists make major breakthrough in fighting leukaemia

At the moment I do not know anything more than that quoted, but I am trying to find out a little more.

Regards

Robert




Replied On: Dec 07, 2009 08:44pm
teakbank12

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Hi Robert
I had this come in on my google feeds today....
http://insciences.org/article.php?article_id=7847
Seems interesting, hope we here more soon

Dave



Replied On: Dec 08, 2009 12:18pm
Robert Cork

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I did have an email communication with Prof Hamblin. He did think that it was a minor advance on 13q deletions, but nothing too significant.

Regards

Robert




Replied On: Dec 08, 2009 04:37pm
sassy1261

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Robert, just read the article. I had always been under the impression that a 13q deletion meant that I was not likely to progress very quickly. According to the article it is possible in theory that a large deletion of 13q could lead to a very aggressive form of the disease, which I gather they did not know before. Now I think that this is extremely significant and I will be asking the haematologist about it. Not that I think she is doing a particularly wonderful job, did not do a FISH test until I insisted, then when she gave me the results requested that I stop panicking, which I wasn't, just wanted all info I could. Sandy



Replied On: Dec 08, 2009 05:32pm
adef

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Here is the press release from Southampton University:

http://www.soton.ac.uk/mediacentre/news/2009/dec/09_162.shtml

You will remember that there has been discussion recently about how accurately university press releases reflect scientific thinking.So here is the abstract from the ASH meeting:

http://ash.confex.com/ash/2009/webprogram/Paper21446.html

It sounds as though they were using a method of analysing DNA that is a research tool at the moment and not part of clinical workup.How long for though?

The recent state of knowledge about 13q deletions was discussed last year on CLL topics:

http://www.clltopics.org/Alert/direct_display_alert.php?reqnum=300

Happy reading,

Adrian



Replied On: Dec 08, 2009 10:07pm
sassy1261

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Adrian, thanks so much for that, I do read cll topics, had missed that one, so will be asking the doc about it. Don't think I have a double deletion or I would be feeling worse than I am, but every bit of knowledge is valuable I think, I am in charge of me and I want to know exactly what is going on.

Thanks again

Sandy



Replied On: Dec 16, 2009 04:23pm
janee

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I have a bilateral 13q deletion and should havehad a stemcell transplant in 2007/8 but opted out as was told that my prognosis was better without a transplant as I was mutated and that meant a good prognosis.Now I am concerned that all I was told has now backfired and things will go downhill fromnow.Iam in C.R at the moment and all my counts are normal,I also had a total hip replacement last January due to arthritis which could have been enhanced by the FCR I had in 2006/7.Any views on this



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